Network-based methods for human disease gene prediction
نویسندگان
چکیده
منابع مشابه
Network-based methods for human disease gene prediction.
Despite the considerable progress in disease gene discovery, we are far from uncovering the underlying cellular mechanisms of diseases since complex traits, even many Mendelian diseases, cannot be explained by simple genotype-phenotype relationships. More recently, an increasingly accepted view is that human diseases result from perturbations of cellular systems, especially molecular networks. ...
متن کاملNetwork-basedmethods for human disease gene prediction
Despite the considerable progress in disease gene discovery, we are far from uncovering the underlying cellular mechanisms of diseases since complex traits, even many Mendelian diseases, cannot be explained by simple genotype^phenotype relationships. More recently, an increasingly accepted view is that human diseases result from perturbations of cellular systems, especially molecular networks. ...
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ژورنال
عنوان ژورنال: Briefings in Functional Genomics
سال: 2011
ISSN: 2041-2649,2041-2657
DOI: 10.1093/bfgp/elr024